Andrew R. Lynch
Postdoctoral Fellow, Cancer Genomics and Evolution Laboratory
The University of Texas MD Anderson Cancer Center
Positions
Genomic instability, tumor evolution, and phenotypic plasticity.
Genomics, computation, and cell and molecular biology to improve measures of chromosomal instability in cancer.
Provided guidance, care, and companionship to survivors of traumatic brain injury.
Used 2D NMR to probe the antigenic potential of MUC1 mimotopes.
Mentored REU participants in laboratory safety, basic biochemistry, solid phase peptide synthesis, and NMR analysis.
Laboratory and field work characterizing domiciliary triatomine species carrying Trypanosoma cruzi.
Training
Thesis: “Quantifying Chromosomal Instability: from first principles toward clinical value.”
Grants & Awards
Service
Publications
Baker, T. M., Lai, S., Lynch, A. R., Lesluyes, T., Yan, H., Ogilvie, H. A., Verfaillie, A., Dentro, S., Bowes, A. L., Pillay, N., Flanagan, A. M., Swanton, C., Spellman, P. T., Tarabichi, M., & Van Loo, P. (2024). The History of Chromosomal Instability in Genome-Doubled Tumors. Cancer Discovery, OF1-OF13.
Lynch, A. R., Bradford, S., Zhou, A. S., Oxendine, K., Henderson, L., Horner, V. L., Weaver, B. A., & Burkard, M. E. (2024). A survey of chromosomal instability measures across mechanistic models. PNAS, 121(16), e2309621121.
Lynch, A., Bradford, S., & Burkard, M. E. (2024). The reckoning of chromosomal instability: past, present, future. Chromosome Research, 32(1), 2.
Zhou, A. S., Tucker, J. B., Scribano, C. M., Lynch, A. R., Carlsen, C. L., Pop-Vicas, S. T., Pattaswamy, S. M., Burkard, M. E., & Weaver, B. A. (2023). Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles. PLOS Biology, 21(10), e3002339.
Lynch, A. R., Arp, N. L., Zhou, A. S., Weaver, B. A., & Burkard, M. E. (2022). Quantifying chromosomal instability from intratumoral karyotype diversity using agent-based modeling and Bayesian inference. eLife, 11, e69799.
Yang, T., Her, C., Lynch, A. R., White, R. J., Wang, M., & Westler, W. M. (2015). Short Proline-Substituted Muc1 Mucin Peptides Can Bind To Mouse Muc1 Monoclonal Antibody as Revealed by STD NMR. Journal of Undergraduate Chemistry Research, 14(1), 5-11.
Updated: 2026-09-15